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Addgene inc pmxs retroviral expression vector
Pmxs Retroviral Expression Vector, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Addgene inc sox2
Sox2, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Addgene inc klf4
Figure 5. The reprogramming potentials of mutant p53 are allele specific. p53 missense mutant cells (10)3.143, (10)3.175, (10)3.273, (10)3.248, (10).281, and control p53 null cell (10)3 were reprogrammed by either 4 factors (Oct4, Sox2, <t>Klf4,</t> and c-Myc) cocktail or 3 factors (Oct4, Sox2, and Klf4) cocktail. A, when reprogrammed by 4 factors, most of the p53 missense mutation exhibited significant lower efficiency except (10) 3.273. B, when reprogrammed by 3 factors, 3 mutations, (10)3.143 (indicated by ), (10)3.175 (indicated by ), and (10)3.273 exhibited higher efficiencies than (10)3 p53 null cells. No iPSC colonies can be detected from (10)3.248 and (10)3.281 cells by 3 factors cocktail.
Klf4, supplied by Addgene inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Addgene inc noboru mizushima
Figure 5. The reprogramming potentials of mutant p53 are allele specific. p53 missense mutant cells (10)3.143, (10)3.175, (10)3.273, (10)3.248, (10).281, and control p53 null cell (10)3 were reprogrammed by either 4 factors (Oct4, Sox2, <t>Klf4,</t> and c-Myc) cocktail or 3 factors (Oct4, Sox2, and Klf4) cocktail. A, when reprogrammed by 4 factors, most of the p53 missense mutation exhibited significant lower efficiency except (10) 3.273. B, when reprogrammed by 3 factors, 3 mutations, (10)3.143 (indicated by ), (10)3.175 (indicated by ), and (10)3.273 exhibited higher efficiencies than (10)3 p53 null cells. No iPSC colonies can be detected from (10)3.248 and (10)3.281 cells by 3 factors cocktail.
Noboru Mizushima, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Addgene inc pmxs ip egfp mulk1
Figure 5. The reprogramming potentials of mutant p53 are allele specific. p53 missense mutant cells (10)3.143, (10)3.175, (10)3.273, (10)3.248, (10).281, and control p53 null cell (10)3 were reprogrammed by either 4 factors (Oct4, Sox2, <t>Klf4,</t> and c-Myc) cocktail or 3 factors (Oct4, Sox2, and Klf4) cocktail. A, when reprogrammed by 4 factors, most of the p53 missense mutation exhibited significant lower efficiency except (10) 3.273. B, when reprogrammed by 3 factors, 3 mutations, (10)3.143 (indicated by ), (10)3.175 (indicated by ), and (10)3.273 exhibited higher efficiencies than (10)3 p53 null cells. No iPSC colonies can be detected from (10)3.248 and (10)3.281 cells by 3 factors cocktail.
Pmxs Ip Egfp Mulk1, supplied by Addgene inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Addgene inc pmxs ip gfp human nbr1
Figure 5. The reprogramming potentials of mutant p53 are allele specific. p53 missense mutant cells (10)3.143, (10)3.175, (10)3.273, (10)3.248, (10).281, and control p53 null cell (10)3 were reprogrammed by either 4 factors (Oct4, Sox2, <t>Klf4,</t> and c-Myc) cocktail or 3 factors (Oct4, Sox2, and Klf4) cocktail. A, when reprogrammed by 4 factors, most of the p53 missense mutation exhibited significant lower efficiency except (10) 3.273. B, when reprogrammed by 3 factors, 3 mutations, (10)3.143 (indicated by ), (10)3.175 (indicated by ), and (10)3.273 exhibited higher efficiencies than (10)3 p53 null cells. No iPSC colonies can be detected from (10)3.248 and (10)3.281 cells by 3 factors cocktail.
Pmxs Ip Gfp Human Nbr1, supplied by Addgene inc, used in various techniques. Bioz Stars score: 88/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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93
Addgene inc akt plasmids
Figure 5. The reprogramming potentials of mutant p53 are allele specific. p53 missense mutant cells (10)3.143, (10)3.175, (10)3.273, (10)3.248, (10).281, and control p53 null cell (10)3 were reprogrammed by either 4 factors (Oct4, Sox2, <t>Klf4,</t> and c-Myc) cocktail or 3 factors (Oct4, Sox2, and Klf4) cocktail. A, when reprogrammed by 4 factors, most of the p53 missense mutation exhibited significant lower efficiency except (10) 3.273. B, when reprogrammed by 3 factors, 3 mutations, (10)3.143 (indicated by ), (10)3.175 (indicated by ), and (10)3.273 exhibited higher efficiencies than (10)3 p53 null cells. No iPSC colonies can be detected from (10)3.248 and (10)3.281 cells by 3 factors cocktail.
Akt Plasmids, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Addgene inc pmxs ip egfp ulk2
Figure 5. The reprogramming potentials of mutant p53 are allele specific. p53 missense mutant cells (10)3.143, (10)3.175, (10)3.273, (10)3.248, (10).281, and control p53 null cell (10)3 were reprogrammed by either 4 factors (Oct4, Sox2, <t>Klf4,</t> and c-Myc) cocktail or 3 factors (Oct4, Sox2, and Klf4) cocktail. A, when reprogrammed by 4 factors, most of the p53 missense mutation exhibited significant lower efficiency except (10) 3.273. B, when reprogrammed by 3 factors, 3 mutations, (10)3.143 (indicated by ), (10)3.175 (indicated by ), and (10)3.273 exhibited higher efficiencies than (10)3 p53 null cells. No iPSC colonies can be detected from (10)3.248 and (10)3.281 cells by 3 factors cocktail.
Pmxs Ip Egfp Ulk2, supplied by Addgene inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Figure 5. The reprogramming potentials of mutant p53 are allele specific. p53 missense mutant cells (10)3.143, (10)3.175, (10)3.273, (10)3.248, (10).281, and control p53 null cell (10)3 were reprogrammed by either 4 factors (Oct4, Sox2, <t>Klf4,</t> and c-Myc) cocktail or 3 factors (Oct4, Sox2, and Klf4) cocktail. A, when reprogrammed by 4 factors, most of the p53 missense mutation exhibited significant lower efficiency except (10) 3.273. B, when reprogrammed by 3 factors, 3 mutations, (10)3.143 (indicated by ), (10)3.175 (indicated by ), and (10)3.273 exhibited higher efficiencies than (10)3 p53 null cells. No iPSC colonies can be detected from (10)3.248 and (10)3.281 cells by 3 factors cocktail.
Ins 832 13 Cells, supplied by Addgene inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Addgene inc pmxs ip egfp matg5
Figure 5. The reprogramming potentials of mutant p53 are allele specific. p53 missense mutant cells (10)3.143, (10)3.175, (10)3.273, (10)3.248, (10).281, and control p53 null cell (10)3 were reprogrammed by either 4 factors (Oct4, Sox2, <t>Klf4,</t> and c-Myc) cocktail or 3 factors (Oct4, Sox2, and Klf4) cocktail. A, when reprogrammed by 4 factors, most of the p53 missense mutation exhibited significant lower efficiency except (10) 3.273. B, when reprogrammed by 3 factors, 3 mutations, (10)3.143 (indicated by ), (10)3.175 (indicated by ), and (10)3.273 exhibited higher efficiencies than (10)3 p53 null cells. No iPSC colonies can be detected from (10)3.248 and (10)3.281 cells by 3 factors cocktail.
Pmxs Ip Egfp Matg5, supplied by Addgene inc, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Figure 5. The reprogramming potentials of mutant p53 are allele specific. p53 missense mutant cells (10)3.143, (10)3.175, (10)3.273, (10)3.248, (10).281, and control p53 null cell (10)3 were reprogrammed by either 4 factors (Oct4, Sox2, Klf4, and c-Myc) cocktail or 3 factors (Oct4, Sox2, and Klf4) cocktail. A, when reprogrammed by 4 factors, most of the p53 missense mutation exhibited significant lower efficiency except (10) 3.273. B, when reprogrammed by 3 factors, 3 mutations, (10)3.143 (indicated by ), (10)3.175 (indicated by ), and (10)3.273 exhibited higher efficiencies than (10)3 p53 null cells. No iPSC colonies can be detected from (10)3.248 and (10)3.281 cells by 3 factors cocktail.

Journal: Cancer Research

Article Title: Multiple Roles of p53-Related Pathways in Somatic Cell Reprogramming and Stem Cell Differentiation

doi: 10.1158/0008-5472.can-12-1451

Figure Lengend Snippet: Figure 5. The reprogramming potentials of mutant p53 are allele specific. p53 missense mutant cells (10)3.143, (10)3.175, (10)3.273, (10)3.248, (10).281, and control p53 null cell (10)3 were reprogrammed by either 4 factors (Oct4, Sox2, Klf4, and c-Myc) cocktail or 3 factors (Oct4, Sox2, and Klf4) cocktail. A, when reprogrammed by 4 factors, most of the p53 missense mutation exhibited significant lower efficiency except (10) 3.273. B, when reprogrammed by 3 factors, 3 mutations, (10)3.143 (indicated by ), (10)3.175 (indicated by ), and (10)3.273 exhibited higher efficiencies than (10)3 p53 null cells. No iPSC colonies can be detected from (10)3.248 and (10)3.281 cells by 3 factors cocktail.

Article Snippet: Retroviral vectors encoding each of the mouse genes OCT4, SOX2, C-MYC, and KLF4 (15918, 15919, 15920, 15921, deposited by Dr. Shinya Yamanaka's laboratory) and retroviral packaging plasmid pLCECO (12371, developed by Dr Inder Verma's laboratory) were obtained from Addgene. pMX-GFP was purchased from Cell Biolabs.

Techniques: Mutagenesis, Control